Computing Discoveries on the Genome

David Lipman

Researchers now have access to a complete draft sequence of the human genome, over two-thirds of the human genome is very-high-quality finished sequence, and a draft sequence of the mouse genome is also publicly available. A wide array of genes, maps, markers, and other genomic reagents have been aligned to these genomes and are available on several Web sites that should prove useful to researchers studying epigenetics. The National Center for Biotechnology Information (NCBI) provides access to these genomic resources as well as views of the whole genomes of more than 800 organisms. We will provide an overview of these integrated resources and related services at the NCBI and some examples of how these may be used to make biological discoveries.